Recurrent Malignant Melanoma Detected on 18F-Fluciclovine PET/CT Imaging for Prostate Cancer
نویسندگان
چکیده
منابع مشابه
Imaging of recurrent prostate cancer.
Approximately 30% of patients who underwent radical prostatectomy or radiation therapy will develop biochemical recurrent disease. Biochemical recurrent disease is defined as an increase in the serum value of prostate-specific antigen (PSA) after reaching the nadir. Prostate recurrence can present as PSA-only relapse, local recurrent disease, distant metastases, or a combination of local and di...
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Primary malignant melanoma of uterine cervix is extremely rare malignancy with very few case published reports. This neoplasm is having poor prognosis, so early diagnosis, staging and treatment is of extreme importance. 18F-FDG PET-CT (18F-labeled fluoro-2-deoxyglucose positron emission computed tomography) scan is an established modality to determine exact extent of disea...
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Metastatic malignant melanoma of the prostate is extremely rare in clinical practice, and only one case has been reported in the English literature in the past 30 years. We report a case of malignant melanoma that metastasized to the prostate and review the current literature. A 50-year-old man with a history of malignant melanoma metastasis to the left axilla, which was excised 3 years ago, pr...
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T hrough its Priority Review mechanism, the U.S. Food and Drug Administration (FDA) recently approved 2 radiopharmaceutical products for use as diagnostic PET agents. The first, approved on May 27, was Axumin (18F-fluciclovine) injection, indicated for use in PET imaging to identify suspected sites of prostate cancer recurrence in men with elevated levels of prostate-specific antigen (PSA) foll...
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[18F]Fluciclovine (trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid; anti-[18F]FACBC), a positron emission tomography tracer used for the diagnosis of recurrent prostate cancer, is transported via amino acid transporters (AATs) with high affinity (Km: 97-230 μM). However, the mechanism underlying urinary excretion is unknown. In this study, we investigated the involvement of AATs and drug ...
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ژورنال
عنوان ژورنال: Clinical Nuclear Medicine
سال: 2017
ISSN: 0363-9762
DOI: 10.1097/rlu.0000000000001789